Bio-Gene is an Australian AgTech company with a novel technology platform based on the naturally occurring class of plant compounds known as beta-triketones that seeks to address the global problem of insecticide resistance and toxicity. Beta-triketone compounds have demonstrated insecticidal activity (e.g. kill or knock down insects) via a novel mode of action in testing performed to date. The insecticidal activity of this beta-triketone chemical class was first discovered following a botanical screening program looking to identify natural product-based insecticides in Australian flora.

Bio-Gene is developing two products targeted at different sectors of the insecticide market:

  • Flavocide™, a chemically synthesised product based on flavesone, a nature identical compound  found in plants of the family Myrtaceae  that includes myrtles and eucalpyts; and
  • Qcide™, derived from a natural oil product containing tasmanone as the main active constituent and extracted from the leaves of a rare cultivar of an Australian eucalypt, the Gympie Messmate (Eucalyptus cloeziana).

Flavocide and Qcide have been developed by Bio-Gene to address the major worldwide problem of insecticide resistance in the areas of crop protection, animal health, public health and consumer applications.

Both products have been shown to have promising insecticidal activity against a broad range of insects known to cause damage to agricultural crops such as aphids and mites; insects which affect animals such as ticks in cattle ; and against insects causing major public health issues such as flies and mosquitoes including Anopheles mosquitoes that transmit malaria, and Aedes mosquitoes that are  vectors for Zika and Dengue viruses. Studies have shown that Flavocide and Qcide act effectively on resistant insect populations indicating a unique mode of action.

Bio-Gene owns patents covering the use of these beta-triketone insecticides for insect control.

The Company is continuing to evaluate these two products against other insects in laboratory and field situations.

Both of these beta-triketones may potentially be used alone, or in combination with other insecticides, with targeted applications in insect pest management and insecticide resistance management programs.